Lidocaine ndi mankhwala am'deralo, omwe amadziwikanso kuti sirocaine, omwe alowa m'malo mwa procaine m'zaka zaposachedwa ndipo amagwiritsidwa ntchito kwambiri popanga opaleshoni yodzikongoletsa.Imalepheretsa chisangalalo cha minyewa ndi kuwongolera mwa kuletsa njira za sodium ion mu nembanemba zama cell.Kusungunuka kwake kwa lipids ndi kuchuluka kwa mapuloteni ndi apamwamba kuposa a procaine, omwe ali ndi mphamvu zolowera m'maselo, amayamba mofulumira, nthawi yayitali yochitapo kanthu, komanso kuchitapo kanthu kuwirikiza kanayi kuposa procaine.
Ntchito zachipatala zimaphatikizapo kulowetsedwa kwa anesthesia, epidural anesthesia, anesthesia pamtunda (kuphatikizapo mucosal anesthesia panthawi ya thoracoscopy kapena opaleshoni ya m'mimba), ndi mitsempha ya conduction block.Pofuna kutalikitsa nthawi ya opaleshoni ndi kuchepetsa mavuto monga lidocaine wa poyizoni, adrenaline akhoza kuwonjezeredwa mankhwala ochititsa.
Lidocaine angagwiritsidwenso ntchito pofuna kuchiza yamitsempha yamagazi kumenyedwa msanga, yamitsempha yamagazi tachycardia, digitalis poizoni, yamitsempha yamagazi arrhythmias chifukwa cha opaleshoni mtima ndi catheterization pambuyo pachimake m`mnyewa wamtima infarction, kuphatikizapo yamitsempha yamagazi kumenyedwa msanga, yamitsempha yamagazi tachycardia, ndi yamitsempha yamagazi fibrillation amagwiritsidwanso ntchito. ndi khunyu kosatha omwe sagwira ntchito ndi anticonvulsants ena komanso opaleshoni yapafupi kapena ya msana.Koma nthawi zambiri sizithandiza pa supraventricular arrhythmias.
Kafukufuku akupita patsogolo pa perioperative mtsempha kulowetsedwa wa lidocaine wa kulowetsedwa
Kugwiritsa ntchito mankhwala opioid pafupipafupi kumatha kuyambitsa zovuta zingapo, zomwe zimalimbikitsa kufufuza mozama pamankhwala omwe si a opioid.Lidocaine ndi imodzi mwamankhwala othandiza kwambiri omwe si opioid analgesic.Perioperative makonzedwe a lidocaine wa kuchepetsa intraoperative mlingo wa opioid mankhwala, kuthetsa ululu postoperative, imathandizira pambuyo opaleshoni kuchira m`mimba ntchito, kufupikitsa kutalika kwa chipatala ndi kulimbikitsa postoperative kukonzanso.
Kuchipatala ntchito mtsempha wa magazi lidocaine wa pa perioperative nthawi
1.Kuchepetsa kupsinjika maganizo panthawi ya opaleshoni ya anesthesia
2. kuchepetsa mlingo wa intraoperative wa mankhwala opioid, kuthetsa ululu pambuyo opaleshoni
3.Limbikitsani kubwezeretsa ntchito ya m'mimba, kuchepetsa zochitika za postoperative nseru ndi kusanza (PONV) ndi postoperative cognitive impairment (POCD), ndikufupikitsa chipatala.
4.Zinthu zina
Kuphatikiza pa zomwe tafotokozazi, lidocaine amakhalanso ndi zotsatira zochepetsera ululu wa jekeseni wa propofol, kuletsa kuyankha kwa chifuwa pambuyo potulutsa, komanso kuchepetsa kuwonongeka kwa myocardial.
Nthawi yotumiza: May-17-2023